PROFILE OF DRUG RELATED PROBLEMS (DRPS) IN OUTPATIENT HYPERTENSION PATIENTS AT BAYUNG LENCIR PUBLIC HEALTH CENTER IN 2024

HYPERTENSION
Putri Ayu 1 Indonesia ROR , Siti Marwah Lestari 1 Indonesia ROR
1 Universitas Adiwangsa Jambi ROR
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Published 2026-06-20
Vol. 8 No. 1 (2026) PAGES 167- 178
DOI 10.36566/ijhsrd/Vol8.Iss1/380
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Background; Drug-related problems (DRPs) are events associated with drug therapy, whether actual or potential, that may hinder the achievement of intended health outcomes. This study describes the profile of DRPs occurrences among outpatient hypertensive patients at Bayung Lencir Community Health Center in 2024, based on the Pharmaceutical Care Network Europe (PCNE) classification version 9.1.

Methods: A non-experimental, cross-sectional design with retrospective data collection was employed, utilizing purposive sampling. The identification and evaluation of DRP incidents were conducted based on the PCNE V9.1 classification.

Results: The results show that antihypertensive drug use was predominantly from the Calcium Channel Blocker (CCB) class, particularly amlodipine (86.59%). Among the 82 patients who met the inclusion criteria, 52 experienced DRPs. The primary DRP categories identified were potential suboptimal drug treatment effects (13.89%), untreated indications or symptoms (8.33%), potential adverse drug events (72.22%), and unnecessary drug therapy (4.17%). The incidence of drug-related problems (DRPs) among outpatients with hypertension at the Bayung Lencir Community Health Center remains relatively high, with the most common category being potential adverse drug events.

Conclusion: The results of this study highlight the importance of comprehensive evaluation to improve treatment effectiveness and patient safety.

PROFILE OF DRUG RELATED PROBLEMS (DRPS) IN OUTPATIENT HYPERTENSION PATIENTS AT BAYUNG LENCIR PUBLIC HEALTH CENTER IN 2024: HYPERTENSION. (2026). INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT (IJHSRD), 8(1), 167-178. https://doi.org/10.36566/ijhsrd/Vol8.Iss1/380
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  1. 1. Kemenkes RI. Pedoman Nasional Pelayanan Kedokteran Tata Laksana Hipertensi Dewasa. 2021;1–85.
  2. 2. Dinkes Prov Sumatera Selatan. Profil Kesehatan Provinsi Sumatra Selatan Tahun 2023. 2024;111.
  3. 3. Fitriyani. Identifikasi Drug Related Problems (DRPs) Kategori Interaksi Obat Dengan Obat Terhadap Pasien Hipertensi di RSUD Haji Makassar Prov. Sul-Sel Tahun 2016. 2017;
  4. 4. Puspitasari CE, Widiyastuti R, Dewi NMAR, Woro OQL, Syamsun A. Profil Drug Related Problems (DRPs) pada Pasien Hipertensi di Instalasi Rawat Jalan Rumah Sakit Pemerintah di Kota Mataram Tahun 2018. 2022;4(1):77–87.
  5. 5. PCNE. PCNE Classification for Drug-Related Problems V9.1. Pharmaceutical Care Network Europe Association. 2020;1–10.
  6. 6. Rokiban A, Dwiauliaramdini, Sitijuwariyah. Analisis Drug Related Problems (DRPs) Pada Pasien Rawat Jalan Diabetes Melitus Tipe 2 di UPT Puskesmas Rawat Inap Gedong Air Bandar Lampung. 2020;9.
  7. 7. Amrina S, E.Puspitasari C, Dewi NMAR. Evaluasi DRPs Pada Pasien Hipertensi Rawat Jalan di Puskesmas Tanjung Karang Kota Mataram Tahun 2020. 2020;149.
  8. 8. Mahmudah S, Arini FA, Hidup G, Makan P. Hubungan gaya hidup dan pola makan dengan kejadian hipertensi pada lansia di kelurahan sawangan baru. 2015;7:43–51.
  9. 9. Womsiwor I, Tampa’I R, Kanter JW, Potalnagi NO. Analisis Drug Related Problems (DRPS) Pada Pasien Hipertensi Geriatri Di Puskesmas Rurukan Tomohon. 2023;6(1):25–31.
  10. 10. Khusna N, Murdiana HE. Identifikasi Drug Related Problems ( DRPs ) Obat Antihipertensi Pada Pasien Hipertensi Di Puskesmas Dharma Rini Temanggung. 2021;I.
  11. 11. Kusumiati M, Christiani GJ, Atmaja SP. Evaluasi Drug Related Problems (DRPs) pada Pasien Hipertensi Primer di Puskesmas Depok II Kalasan Sleman. 2024;9(1):16–22.
  12. 12. Firiansyah AR, Amir SP, Muchtar A, Hidayati PH, Nur MJ. Karakteristik Sindrom Dispepsia pada Mahasiswa Angkatan 2021 Fakultas Kedokteran Universitas Muslim Indonesia. 2021;680–8.
  13. 13. Husni H, Wahyudin E, Kasim H. Hubungan Tekanan Darah Sistolik dengan Kadar HBA1C Pada Pasien Hipertensi dan Diabetes Melitus Type 2 di RS Unhas Makassar. 2022;26(2):84–7.
  14. 14. Julianti IMD. Hubungan Antara Kadar Gula Darah Dengan Tekanan Darah Pada Pasien Diabetes Melitus Tipe II. 2021;1–7.
  15. 15. Putri MPD, Suyasa IPGA, Budiapsari PI. Hubungan antara Dislipidemia dengan Kejadian Hipertensi di Bali Tahun 2019. 2021;1(1).
  16. 16. Sylvestris A. Hipertensi dan Retinopati Hipertensi. 2014;10.
  17. 17. Febriani CF, Sutrisno, Santoni I. Hubungan Antara Hiperurisemia Dengan Kejadian Hipertensi Pada Lansia. 2018;6(2):36–42.
  18. 18. Kurniawana A, Aktalinab L, Syahputrab B, Risnawatib R. Karakteristik Hipertensi dan Peningkatan Asam Urat di Puskesmas Medan Amplas. 2024;23(2):155–60.
  19. 19. Hermawati L, Zulfa HA, Irawati NBU, Diana WA. Hiperurisemia dan Hipertensi : Hubungan, Mekanisme, dan Implikasi Klinis – Review Artikel. 2025;13:1–9.
  20. 20. Pendit SA, Reti H. Faktor-Faktor yang Mempengaruhi Nyeri Berulang Pada Paien Lansia dengan Osteoarthitis di Poli Geriatri. 2023;12(2):287–97.
  21. 21. Parulian L, Listyanti E, Hati AK, Sunnah I. Analisis Hubungan Polifarmasi Dan Interaksi Obat Pada Pasien Rawat Jalan Yang Mendapat Obat Hipertensi Di Rsp. Dr. Ario Wirawan Periode Januari-Maret 2019. 2019;02(September):79–86.
  22. 22. Adiana S, Maulina D. Klasifikasi Permasalahan Terkait Obat ( Drug Related Problem/DRPs): Review. 2022;2(2):54–8.
  23. 23. Ridwan BA, Rachmah IM, Waluya UM, Darah TT. Hubungan Kejadian Drug Related Problems ( DRPs ) Dengan Ketercapaian Target Tekanan Darah Pasien Hipertensi DI Puskesmas Lalonggasumeeto Kabupaten Konawe. 2023;III(September):103–13.
  24. 24. Wildan MM, Rahayuningsih N, Salasanti CD. Karakteristik Pasien dan Penggunaan Obat Hipertensi di Beberapa Sarana Kesehatan. 2025;14(3).
  25. 25. Khoerunnisa V, Suryanti L, Syafi I. Hubungan Tingkat Pengetahuan Pasien Hipertensi Terhadap Kepatuhan Minum Obat Antihipertensi di Klinik Herlina Cianjur. 2025;03(01):28–36.
  26. 26. Tuloli TS, Pakaya MS, Pratiwi SD. Identifikasi Drug Related Problems ( DRPs ) Pasien Hipertensi di RS Multazam Kota Gorontalo. 2021;1(1):1–9.
  27. 27. Saidina TM. Studi Kasus Hernia Inguinalis Lateralis pada Laki-laki Usia 51 Tahun. 2025;(4).
  28. 28. Idacahyati K, Nofianti T, Aswa GA, Nurfatwa M. Hubungan Tingkat Kejadian Efek Samping Antiinflamasi Non Steroid dengan Usia dan Jenis Kelamin. 2020;6(2):56–61.
  29. 29. Ramadani N. Penerapan Pemberian Kompres Hangat Pada Tengkuk Terhadap Penurunan Intensitas Nyeri Kepala Pada Pasien Hipertensi Di Rsud Labuan.pdf. 2023;1–5.
  30. 30. Mariam S, Y AS, Kurniasih N. Evaluasi Kejadian Interaksi Obat Antihipertensi Pada Pasien Rawat Jalan Di Puskesmas Tanah Sareal. 2022;7(2):157–64.
  31. 31. Habibi BY. Terapi Pada Dispepsia. 2021;3:503–10.
  32. 32. Mahamudu YS, Citraningtyas G, Rotinsulu H. Kajian Potensi Interaksi Obat Antihipertensi Pada Paien Hipertensi Primer Di Instalasi Rawat Jalan RSUD Luwuk Periode Januari-Maret 2016. 2017;6(3):1–9.
  33. 33. Astini SP, Nyoman N, Udayani W, Meriyani H. Studi Retrospektif Penggunaan Obat Dan Potensi Interaksi Obat Pasien Systemic Lupus Erythematosus. 2021;7(2):77–83.
  34. 34. Roni RK, Ulfa AM, Rudy M. Potensi Interaksi Obat Anthipertensi Di Puskesmas Pinang Jaya Menggunakan Metode Observasi. 2023;10(11):3281–93.
  35. 35. Puspita S, Febriana S, F NN, Putra RP, Ratnawati R, Wulandari AE. Evaluasi Penggunaan Obat PPI (Pump Proton Inhibitor) Pada Pasien Rawat Inap Di RSAU dr. EFRAM HARSANA LANUD ISWAHJUDI Magetan. 2025;4:220–31.
  36. 36. Noviyanto F, Pertiwi R, Shobah AN. Evaluasi Terapi Kortikosteroid Oral pada Pasien Asma di Rumah Sakit Drajat Prawiranegara Tahun 2022. 2025;22(01):1–4.
  37. 37. Sa’diyah M, Susiyarti, Sari MP. Tingkat Pengetahuan Bahaya Penggunaan Kortikosteroid yang Tidak Rasional di Apotek Duta Sehat. 2026;7:4613–21.
  38. 38. Kemenkes RI. (2011). Modul Penggunaan Obat Rasional (POR)
  39. 39. Tjay, T.H., & Rahardja, K. (2015). Obat-obat Penting : Khasiat, Penggunaan dan Efek-Efek Sampingnya (Edisi ke-7). Jakarta: PT Elex Media Komputindo.

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Keywords
Community Health Center drug-related problems PCNE Hypertension outpatient

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