CORRELATION BETWEEN FOOD QUALITY AND MICROBIOTA PROFILE OF PREGNANT WOMEN IN THE CITY OF PADANG

FOOD QUALITY AND MICROBIOTA PROFILE
Rizka Yulia Sary 1 Indonesia , Helmizar Helmizar 2 Indonesia , Andani Eka Putra 2 Indonesia
1 a:1:{s:5:"en_US";s:18:"Andalas univeristy";}
2 Andalas univeristy
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Published 2025-12-24
Vol. 7 No. 2 (2025) PAGES 40-48
DOI 10.36566/ijhsrd/Vol7.Iss2/316
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Background:

Pregnancy is a complex physiological period that requires systemic adaptation of the body. During pregnancy, a balanced blood microbiota plays an important role in maintaining the mother's immune system and supporting fetal development. This study aims to determine the correlation between food quality and the microbiota profile of pregnant women in Padang City.

Methods: This is an observational study with a cross-sectional design. The study was conducted from January to March 2025 at the Centre for Diagnostic and Research on Infectious Diseases (PDRPI) Laboratory, Andalas University. The sample size was 20 participants, selected using total sampling. Microbiota profiling was performed using 16S rRNA metagenomic sequencing. The results of the microbiota profile analysis were analyzed using Microbiome Analysist software.

Results: Statistical analysis showed a p-value of 0.14702 and a t-statistic of -1.5182, indicating that there was no statistically significant difference between food quality and microbiota profile. The comparison of the Firmicutes/Bacteroidetes ratio (F/B ratio) was 1.06, indicating a balanced microbiota in pregnant women.

Conclusion: Although not statistically significant, these differences in microbiota composition are biologically important and suggest a potential association between dietary patterns and systemic health in pregnant women.

CORRELATION BETWEEN FOOD QUALITY AND MICROBIOTA PROFILE OF PREGNANT WOMEN IN THE CITY OF PADANG : FOOD QUALITY AND MICROBIOTA PROFILE . (2025). INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT (IJHSRD), 7(2), 40-48. https://doi.org/10.36566/ijhsrd/Vol7.Iss2/316
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  1. 1. Amato KR, Pradhan P, Mallott EK, Shirola W, Lu A. Host–gut microbiota interactions during pregnancy. Vol. 12, Evolution, Medicine and Public Health. Oxford University Press; 2024. p. 7–23.
  2. 2. Castillo DJ, Rifkin RF, Cowan DA, Potgieter M. The healthy human blood microbiome: Fact or fiction? Front Cell Infect Microbiol. 2019;9(MAY).
  3. 3. Amar J, Lange C, Payros G, Garret C, Chabo C, Lantieri O, et al. Blood microbiota dysbiosis is associated with the onset of cardiovascular events in a large general population: The D.E.S.I.R. Study. PLoS One. 2013 Jan 30;8(1).
  4. 4. Zheng D, Liwinski T, Elinav E. Interaction between microbiota and immunity in health and disease. Vol. 30, Cell Research. Springer Nature; 2020. p. 492–506.
  5. 5. Panaiotov S, Hodzhev Y, Tsafarova B, Tolchkov V, Kalfin R. Microorganisms culturable and non-culturable blood microbiota of healthy individuals. 2021; Available from: https://doi.org/10.3390/microorganisms9071464
  6. 6. Raeisi J, Oloomi M, Zolfaghari MR, Siadat SD, Zargar M, Pourramezan Z. Bacterial DNA detection in the blood of healthy subjects. Iran Biomed J. 2022 May 1;26(3):230–9.
  7. 7. Kembel SW, Jones E, Kline J, Northcutt D, Stenson J, Womack AM, et al. Architectural design influences the diversity and structure of the built environment microbiome. ISME Journal. 2012 Aug;6(8):1469–79.
  8. 8. Melati Davidson S, Tampubolon R, Berlyana Bornensiska C. Kecukupan gizi dan kejadian anemia ibu hamil di wilayah kerja puskesmas sidorejo lor kota salatiga. Jurnal Gizi. 11(2):2022.
  9. 9. Mariat D, Firmesse O, Levenez F, Guimarǎes VD, Sokol H, Doré J, et al. The firmicutes/bacteroidetes ratio of the human microbiota changes with age. BMC Microbiol. 2009;9.
  10. 10. Magne F, Gotteland M, Gauthier L, Zazueta A, Pesoa S, Navarrete P, et al. The firmicutes/bacteroidetes ratio: A relevant marker of gut dysbiosis in obese patients? Nutrients. 2020 May 1;12(5).
  11. 11. Koren O, Goodrich JK, Cullender TC, Spor A, Laitinen K, Kling Bäckhed H, et al. Host remodeling of the gut microbiome and metabolic changes during pregnancy. Cell. 2012 Aug 3;150(3):470–80.
  12. 12. Clarke SF, Murphy EF, O’Sullivan O, Lucey AJ, Humphreys M, Hogan A, et al. Exercise and associated dietary extremes impact on gut microbial diversity. Gut. 2014 Dec 1;63(12):1913–20.
  13. 13. Nuriel-Ohayon M, Neuman H, Koren O. Microbial changes during pregnancy, birth, and infancy. Vol. 7, Frontiers in Microbiology. Frontiers Media S.A.; 2016.
  14. 14. Arrieta MC, Stiemsma LT, Amenyogbe N, Brown E, Finlay B. The intestinal microbiome in early life: Health and disease. Vol. 5, Frontiers in Immunology. 2014.
  15. 15. Rothschild D, Weissbrod O, Barkan E, Korem T, Zeevi D, Costea PI, et al. Environmental factors dominate over host genetics in shaping human gut microbiota composition. Nature [Internet]. 2017 Jun 16;(555):210–5. Available from: http://biorxiv.org/lookup/doi/10.1101/150540
  16. 16. Morrison DJ, Preston T. Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism. Vol. 7, Gut Microbes. Taylor and Francis Inc.; 2016. p. 189–200.
  17. 17. David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505(7484):559–63.
  18. 18. Flint HJ, Scott KP, Duncan SH, Louis P, Forano E. Microbial degradation of complex carbohydrates in the gut. Vol. 3, Gut Microbes. 2012.
  19. 19. Rinninella E, Raoul P, Cintoni M, Franceschi F, Miggiano GAD, Gasbarrini A, et al. What is the healthy gut microbiota composition? A changing ecosystem across age, environment, diet, and diseases. Microorganisms. 2019 Jan 1;7(1).
  20. 20. Hosseini E, Grootaert C, Verstraete W. Propionate as a health-promoting microbial metabolite in the human gut. Nutr Rev. 2011;69(5).

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Keywords
Diet quality Microbiota profile Pregnant women public health health

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