THE LIVER FUNCTION TEST (TRANSAMINASE ENZYMES AND BILIRUBIN) AND THE KIDNEY FUNCTION TESTS (UREA, CREATININE) ANALYSIS IN MDR-TB DURING TREATMENT

Widaninggar Rahma Putri 1 Indonesia , Havida Widyastuti 1 Indonesia , Dhini Intan Cahyani 1 Indonesia , Wa Ode Hikma Fajar 1 Indonesia
1 Universitas Aisyiyah Yogyakarta
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Published 2026-06-20
Vol. 8 No. 1 (2026) PAGES 109-114
DOI 10.36566/ijhsrd/Vol8.Iss1/370
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Background:

Multi Drug Resistance Tuberculosis (MDR-TB) treatment caused side effects such as hepatotoxicity and acute kidney injury (AKI).  Monitoring liver and kidney function in patients during treatment is crucial to prevent complication.

Methods: A retrospective study of 19 patients confirmed MDR-TB in the period 2022-2025. Liver function test (transaminase enzymes and bilirubin) and kidney function test (urea and creatinine) during the first three month of treatment were analyzed.

Results: Statistically, there was no difference in all parameters (p>0.05). Increases in total bilirubin, SGOT, SGPT levels occurred in the third month of TB treatment. While urea and creatinine levels increased in the second and third months.

Conclusion: Monitoring of liver and kidney function during MDR-TB treatment is necessary to monitor patient condition.

THE LIVER FUNCTION TEST (TRANSAMINASE ENZYMES AND BILIRUBIN) AND THE KIDNEY FUNCTION TESTS (UREA, CREATININE) ANALYSIS IN MDR-TB DURING TREATMENT . (2026). INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT (IJHSRD), 8(1), 109-114. https://doi.org/10.36566/ijhsrd/Vol8.Iss1/370
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Multi Drug Resistance Tuberculosis Liver function Kidney Function

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